TIMP3 interplays with apelin to regulate cardiovascular metabolism in hypercholesterolemic mice

TIMP3 interplays with apelin to regulate cardiovascular metabolism in hypercholesterolemic mice

Objective: Tissue inhibitor of metalloproteinase 3 (TIMP3) is an extracellular matrix (ECM) bound protein, which has been shown to be downregulated in human subjects and experimental models with cardiometabolic disorders, including type 2 diabetes mellitus, hypertension and atherosclerosis. The aim...

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Bibliographic Details
Main Authors: Robert Stöhr, Ben Arpad Kappel, Daniela Carnevale, Michele Cavalera, Maria Mavilio, Ivan Arisi, Valentina Fardella, Giuseppe Cifelli, Viviana Casagrande, Stefano Rizza, Antonino Cattaneo, Alessandro Mauriello, Rossella Menghini, Giuseppe Lembo, Massimo Federici
Format: Article
Language:English
Published: Elsevier 2015-10-01
Series:Molecular Metabolism
Subjects:
TIMP3
Heart
Lipid metabolism
Apelin
Arrhythmia
Oxidative stress
Online Access:http://www.sciencedirect.com/science/article/pii/S2212877815001416

Internet

http://www.sciencedirect.com/science/article/pii/S2212877815001416

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