ABCA1 promotes the efflux of bacterial LPS from macrophages and accelerates recovery from LPS-induced tolerance[S]

ABCA1 promotes the efflux of bacterial LPS from macrophages and accelerates recovery from LPS-induced tolerance[S]

Macrophages play important roles in both lipid metabolism and innate immunity. We show here that macrophage ATP-binding cassette transporter A1 (ABCA1), a transporter known for its ability to promote apolipoprotein-dependent cholesterol efflux, also participates in the removal of an immunostimulator...

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Bibliographic Details
Main Authors: Patricia A. Thompson, Karine C. Gauthier, Alan W. Varley, Richard L. Kitchens
Format: Article
Language:English
Published: Elsevier 2010-09-01
Series:Journal of Lipid Research
Subjects:
ATP-binding cassette transporter A1
apolipoprotein
cytokine
endotoxin
gene reprogramming
immunosuppression
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520422977

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http://www.sciencedirect.com/science/article/pii/S0022227520422977

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