Insulin-loaded polymeric mucoadhesive nanoparticles: development, characterization and cytotoxicity evaluation

Abstract Mucoadhesive nanoparticles are particularly interesting for delivery through nasal or pulmonary routes, as an approach to overcome the mucociliary clearance. Moreover, these nanoparticles are attractive for peptide and protein delivery, particularly for insulin to treat diabetes, as an alte...

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Bibliographic Details
Main Authors: Tiago Henrique Honorato Gatti, Josimar Oliveira Eloy, Leonardo Miziara Barboza Ferreira, Isabel Cristine da Silva, Fernando Rogério Pavan, Maria Palmira Daflon Gremião, Marlus Chorilli
Format: Article
Language:English
Published: Universidade de São Paulo 2018-06-01
Series:Brazilian Journal of Pharmaceutical Sciences
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502018000100623&lng=en&tlng=en