Tonsil-derived mesenchymal stem cell-embedded in situ crosslinkable gelatin hydrogel therapy recovers postmenopausal osteoporosis through bone regeneration.

We investigated therapeutic potential of human tonsil-derived mesenchymal stem cells (TMSC) subcutaneously delivered to ovariectomized (OVX) mice for developing more safe and effective therapy for osteoporosis. TMSC were isolated from tonsil tissues of children undergoing tonsillectomy, and TMSC-emb...

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Bibliographic Details
Main Authors: Gyungah Kim, Yoon Shin Park, Yunki Lee, Yoon Mi Jin, Da Hyeon Choi, Kyung-Ha Ryu, Yoon Jeong Park, Ki Dong Park, Inho Jo
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC6033433?pdf=render