Programmed death ligand-1 and CD8 tumor-infiltrating lymphocytes (TILs) as prognostic predictors in ovarian high-grade serous carcinoma (HGSC)

Programmed death ligand-1 and CD8 tumor-infiltrating lymphocytes (TILs) as prognostic predictors in ovarian high-grade serous carcinoma (HGSC)

Abstract Background P D-L1 is expressed in tumor cells and plays a crucial role in tumor immune escape. Tumor-infiltrating lymphocytes (TILs) as CD8 T cells contribute to reduced tumor growth. Few studies investigated the prognostic effect of PD-L1 and CD8 TILs in ovarian high-grade serous carcinoma...

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Bibliographic Details
Main Authors: Mayada Saad Farrag, Khaled Abdelwahab, Nesrine Saad Farrag, Waleed Elsayed Elrefaie, Ziad Emarah
Format: Article
Language:English
Published: SpringerOpen 2021-07-01
Series:Journal of the Egyptian National Cancer Institute
Subjects:
CD8
HGSC
Immunotherapy
PD-L1
TILs
Online Access:https://doi.org/10.1186/s43046-021-00073-5

Internet

https://doi.org/10.1186/s43046-021-00073-5

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