PACAP and its role in primary headaches

Abstract Pituitary adenylate cyclase-activating peptide (PACAP) is a neuropeptide implicated in a wide range of functions, such as nociception and in primary headaches. Regarding its localization, PACAP has been observed in the sensory trigeminal ganglion (TG), in the parasympathetic sphenopalatine...

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Bibliographic Details
Main Authors: Lars Edvinsson, János Tajti, Levente Szalárdy, László Vécsei
Format: Article
Language:English
Published: BMC 2018-03-01
Series:The Journal of Headache and Pain
Subjects:
Online Access:http://link.springer.com/article/10.1186/s10194-018-0852-4