Antiplasmodial Alkaloids from the Bark of Cryptocarya nigra (Lauraceae)

A dichloromethane extract of the stem bark of Cryptocarya nigra showed strong in vitro inhibition of Plasmodium falciparum growth, with an IC50 value of 2.82 μg/mL. The phytochemical study of this extract has led to the isolation and characterization of four known alkaloids: (+)-N-methylisococlaurin...

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Bibliographic Details
Main Authors: Khalijah Awang, Jamaludin Mohamad, Azeana Zahari, Ayu Afiqah Nasrullah
Format: Article
Language:English
Published: MDPI AG 2013-07-01
Series:Molecules
Subjects:
Online Access:http://www.mdpi.com/1420-3049/18/7/8009