Hyperphosphatemic Tumoral Calcinosis: Pathogenesis, Clinical Presentation, and Challenges in Management

Hyperphosphatemic Tumoral Calcinosis: Pathogenesis, Clinical Presentation, and Challenges in Management

Hyperphosphatemic familial tumoral calcinosis (HFTC) is a rare and disabling disorder of fibroblast growth factor 23 (FGF23) deficiency or resistance. The disorder is manifest by hyperphosphatemia, inappropriately increased tubular reabsorption of phosphate and 1,25-dihydroxy-Vitamin D, and ectopic...

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Bibliographic Details
Main Authors: Alison M. Boyce, Alisa E. Lee, Kelly L. Roszko, Rachel I. Gafni
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-05-01
Series:Frontiers in Endocrinology
Subjects:
fibroblast growth factor 23
phosphate
metabolic bone disease
ectopic calcification
heterotopic ossification
Online Access:https://www.frontiersin.org/article/10.3389/fendo.2020.00293/full

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https://www.frontiersin.org/article/10.3389/fendo.2020.00293/full

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