CGI-58/ABHD5 is phosphorylated on Ser239 by protein kinase A: control of subcellular localization[S]

CGI-58/ABHD5 is phosphorylated on Ser239 by protein kinase A: control of subcellular localization[S]

CGI-58/ABHD5 coactivates adipose triglyceride lipase (ATGL). In adipocytes, CGI-58 binds to perilipin 1A on lipid droplets under basal conditions, preventing interaction with ATGL. Upon activation of protein kinase A (PKA), perilipin 1A is phosphorylated and CGI-58 rapidly disperses into the cytopla...

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Bibliographic Details
Main Authors: Anita Sahu-Osen, Gabriela Montero-Moran, Matthias Schittmayer, Katarina Fritz, Anna Dinh, Yu-Fang Chang, Derek McMahon, Andras Boeszoermenyi, Irina Cornaciu, Deanna Russell, Monika Oberer, George M. Carman, Ruth Birner-Gruenberger, Dawn L. Brasaemle
Format: Article
Language:English
Published: Elsevier 2015-01-01
Series:Journal of Lipid Research
Subjects:
adipocytes
adipose tissue
adipose triglyceride lipase
Chanarin Dorfman syndrome
lipase
lipid droplets
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520356443

Internet

http://www.sciencedirect.com/science/article/pii/S0022227520356443

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