IL-2 immunotherapy reveals potential for innate beta cell regeneration in the non-obese diabetic mouse model of autoimmune diabetes.

IL-2 immunotherapy reveals potential for innate beta cell regeneration in the non-obese diabetic mouse model of autoimmune diabetes.

Type-1 diabetes (T1D) is an autoimmune disease targeting insulin-producing beta cells, resulting in dependence on exogenous insulin. To date, significant efforts have been invested to develop immune-modulatory therapies for T1D treatment. Previously, IL-2 immunotherapy was demonstrated to prevent an...

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Bibliographic Details
Main Authors: Yaiza Diaz-de-Durana, Janet Lau, Deborah Knee, Christophe Filippi, Marco Londei, Peter McNamara, Marc Nasoff, Michael DiDonato, Richard Glynne, Ann E Herman
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3813455?pdf=render

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http://europepmc.org/articles/PMC3813455?pdf=render

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