Cellular Senescence: A Translational Perspective

Cellular Senescence: A Translational Perspective

Cellular senescence entails essentially irreversible replicative arrest, apoptosis resistance, and frequently acquisition of a pro-inflammatory, tissue-destructive senescence-associated secretory phenotype (SASP). Senescent cells accumulate in various tissues with aging and at sites of pathogenesis...

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Bibliographic Details
Main Authors: James L. Kirkland, Tamara Tchkonia
Format: Article
Language:English
Published: Elsevier 2017-07-01
Series:EBioMedicine
Subjects:
Senolytics
SASP inhibitors
Dasatinib
Quercetin
Navitoclax
Fisetin
A1331852
A1155463
Senescent Cell Anti-apoptotic Pathways (SCAPs)
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396417301548

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http://www.sciencedirect.com/science/article/pii/S2352396417301548

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