Elevated Trehalose Levels in <i>C. elegans daf-2</i> Mutants Increase Stress Resistance, Not Lifespan

The <i>C. elegans</i> insulin/IGF-1 signaling mutant <i>daf-2</i> recapitulates the dauer metabolic signature—a shift towards lipid and carbohydrate accumulation—which may be linked to its longevity and stress resistance phenotypes. Trehalose, a disaccharide of glucose, is hi...

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Bibliographic Details
Main Authors: Madina Rasulova, Aleksandra Zečić, Jose Manuel Monje Moreno, Lieselot Vandemeulebroucke, Ineke Dhondt, Bart P. Braeckman
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:Metabolites
Subjects:
Online Access:https://www.mdpi.com/2218-1989/11/2/105