Elevated Trehalose Levels in <i>C. elegans daf-2</i> Mutants Increase Stress Resistance, Not Lifespan
The <i>C. elegans</i> insulin/IGF-1 signaling mutant <i>daf-2</i> recapitulates the dauer metabolic signature—a shift towards lipid and carbohydrate accumulation—which may be linked to its longevity and stress resistance phenotypes. Trehalose, a disaccharide of glucose, is hi...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2021-02-01
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Series: | Metabolites |
Subjects: | |
Online Access: | https://www.mdpi.com/2218-1989/11/2/105 |