Does low-density lipoprotein cholesterol induce inflammation? If so, does it matter? Current insights and future perspectives for novel therapies

Does low-density lipoprotein cholesterol induce inflammation? If so, does it matter? Current insights and future perspectives for novel therapies

Abstract Background Dyslipidemia and inflammation are closely interrelated contributors in the pathogenesis of atherosclerosis. Disorders of lipid metabolism initiate an inflammatory and immune-mediated response in atherosclerosis, while low-density lipoprotein cholesterol (LDL-C) lowering has possi...

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Bibliographic Details
Main Authors: Ruurt A. Jukema, Tarek A. N. Ahmed, Jean-Claude Tardif
Format: Article
Language:English
Published: BMC 2019-11-01
Series:BMC Medicine
Subjects:
Inflammation
Cholesterol
Inflammasome
Immunity
Epigenetics
Atherosclerosis
Online Access:http://link.springer.com/article/10.1186/s12916-019-1433-3

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http://link.springer.com/article/10.1186/s12916-019-1433-3

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