The type 2 diabetes associated minor allele of rs2237895 KCNQ1 associates with reduced insulin release following an oral glucose load.

<h4>Background</h4>Polymorphisms in the potassium channel, voltage-gated, KQT-like subfamily, member 1 (KCNQ1) have recently been reported to associate with type 2 diabetes. The primary aim of the present study was to investigate the putative impact of these KCNQ1 polymorphisms (rs228322...

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Main Authors: Johan Holmkvist, Karina Banasik, Gitte Andersen, Hiroyuki Unoki, Thomas Skot Jensen, Charlotta Pisinger, Knut Borch-Johnsen, Annelli Sandbaek, Torsten Lauritzen, Sören Brunak, Shiro Maeda, Torben Hansen, Oluf Pedersen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-06-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/19516902/?tool=EBI