CC-223, NSC781406, and BGT226 Exerts a Cytotoxic Effect Against Pancreatic Cancer Cells via mTOR Signaling

CC-223, NSC781406, and BGT226 Exerts a Cytotoxic Effect Against Pancreatic Cancer Cells via mTOR Signaling

The mTOR signaling pathway is abnormally activated in pancreatic cancer and is related to tumor glucose metabolism. However, its specific regulation mechanism is still unclear. Therefore, this study aims to investigate whether Sestrin2 affects the glucose metabolism of pancreatic cancer by modulatin...

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Bibliographic Details
Main Authors: Yangyang Guo, Hengyue Zhu, Min Weng, Hewei Zhang, Cheng Wang, Linxiao Sun
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-11-01
Series:Frontiers in Pharmacology
Subjects:
CC-223
NSC781406
BGT226
mTOR
pancreatic cancer
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2020.580407/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2020.580407/full

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