Early responses of the STAT3 pathway to platinum drugs are associated with cisplatin resistance in epithelial ovarian cancer

Cisplatin resistance remains one of the major obstacles when treating epithelial ovarian cancer. Because oxaliplatin and nedaplatin are effective against cisplatin-resistant ovarian cancer in clinical trials and signal transducer and activator of transcription 3 (STAT3) is associated with cisplatin...

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Bibliographic Details
Main Authors: W.J. Sheng, H. Jiang, D.L. Wu, J.H. Zheng
Format: Article
Language:English
Published: Associação Brasileira de Divulgação Científica 2013-08-01
Series:Brazilian Journal of Medical and Biological Research
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2013000800650&lng=en&tlng=en