Inhibition of IRE1 modifies effect of glucose deprivation on the expression of TNFα-related genes in U87 glioma cells

Inhibition of IRE1 modifies effect of glucose deprivation on the expression of TNFα-related genes in U87 glioma cells

Inhibition of IRE1 (inositol requiring enzyme-1), the major signaling pathway of endoplasmic reticulum stress, significantly decreases glioma cell proliferation and tumor growth. We have studied the expression of TNFα-related genes and effect of glucose deprivation on these gene expressions in U87 g...

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Bibliographic Details
Main Authors: I. V. Kryvdiuk, D. O. Minchenko, N. A. Hlushchak, O. O. Ratushna, L. L. Karbovskyi, O. H. Minchenko
Format: Article
Language:English
Published: National Academy of Sciences of Ukraine and Palladin Institute of Biochemistry of the National Academy of Sciences of Ukraine. 2015-11-01
Series:Ukrainian Biochemical Journal
Subjects:
endoplasmic reticulum stress
glioma cells
glucose deprivation
IRE1 inhibition
LITAF
mRNA expression
TNFAIP1
TNFAIP3
TNFRSF10B/DR5
TNFRSF10D
TNFRSF11B
TNFRSF1A
TNFRSF21/DR6
TRADD
Online Access:http://ukrbiochemjournal.org/wp-content/uploads/2015/12/Kryvdiuk_6_15.pdf

Internet

http://ukrbiochemjournal.org/wp-content/uploads/2015/12/Kryvdiuk_6_15.pdf

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