Curcumin restores mitochondrial functions and decreases lipid peroxidation in liver and kidneys of diabetic db/db mice

Curcumin restores mitochondrial functions and decreases lipid peroxidation in liver and kidneys of diabetic db/db mice

BACKGROUND: Nitrosative and oxidative stress play a key role in obesity and diabetes-related mitochondrial dysfunction. The objective was to investigate the effect of curcumin treatment on state 3 and 4 oxygen consumption, nitric oxide (NO) synthesis, ATPase activity and lipid oxidation in mitochond...

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Bibliographic Details
Main Authors: María G Soto-Urquieta, Sergio López-Briones, Victoriano Pérez-Vázquez, Alfredo Saavedra-Molina, Gloria A González-Hernández, Joel Ramírez-Emiliano
Format: Article
Language:English
Published: BMC 2014-01-01
Series:Biological Research
Subjects:
Diabetes
Mitochondria
Curcumin
ATPase activity
Nitric oxide synthesis
Lipid oxidation
Online Access:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602014000100068&lng=en&tlng=en

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http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602014000100068&lng=en&tlng=en

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