A zebrafish-centric approach to antiepileptic drug development
Danio rerio (zebrafish) are a powerful experimental model for genetic and developmental studies. Adaptation of zebrafish to study seizures was initially established using the common convulsant agent pentylenetetrazole (PTZ). Larval PTZ-exposed zebrafish exhibit clear behavioral convulsions and abnor...
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Format: | Article |
Language: | English |
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The Company of Biologists
2021-07-01
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Series: | Disease Models & Mechanisms |
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Online Access: | http://dmm.biologists.org/content/14/7/dmm049080 |