Bistable expression of virulence genes in salmonella leads to the formation of an antibiotic-tolerant subpopulation.

Bistable expression of virulence genes in salmonella leads to the formation of an antibiotic-tolerant subpopulation.

Phenotypic heterogeneity can confer clonal groups of organisms with new functionality. A paradigmatic example is the bistable expression of virulence genes in Salmonella typhimurium, which leads to phenotypically virulent and phenotypically avirulent subpopulations. The two subpopulations have been...

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Bibliographic Details
Main Authors: Markus Arnoldini, Ima Avalos Vizcarra, Rafael Peña-Miller, Nicolas Stocker, Médéric Diard, Viola Vogel, Robert E Beardmore, Wolf-Dietrich Hardt, Martin Ackermann
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-08-01
Series:PLoS Biology
Online Access:http://europepmc.org/articles/PMC4138020?pdf=render

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http://europepmc.org/articles/PMC4138020?pdf=render

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