Bistable expression of virulence genes in salmonella leads to the formation of an antibiotic-tolerant subpopulation.
Phenotypic heterogeneity can confer clonal groups of organisms with new functionality. A paradigmatic example is the bistable expression of virulence genes in Salmonella typhimurium, which leads to phenotypically virulent and phenotypically avirulent subpopulations. The two subpopulations have been...
Main Authors: | , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2014-08-01
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Series: | PLoS Biology |
Online Access: | http://europepmc.org/articles/PMC4138020?pdf=render |