Conditional inactivation of PDCD2 induces p53 activation and cell cycle arrest

Conditional inactivation of PDCD2 induces p53 activation and cell cycle arrest

PDCD2 (programmed cell death domain 2) is a highly conserved, zinc finger MYND domain-containing protein essential for normal development in the fly, zebrafish and mouse. The molecular functions and cellular activities of PDCD2 remain unclear. In order to better understand the functions of PDCD2 in...

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Bibliographic Details
Main Authors: Celine J. Granier, Wei Wang, Tiffany Tsang, Ruth Steward, Hatem E. Sabaawy, Mantu Bhaumik, Arnold B. Rabson
Format: Article
Language:English
Published: The Company of Biologists 2014-08-01
Series:Biology Open
Subjects:
PDCD2
Mouse embryo
Cell cycle
Proliferation
ESCs
p53
Online Access:http://bio.biologists.org/content/3/9/821

Internet

http://bio.biologists.org/content/3/9/821

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