LRRK2 expression is enriched in the striosomal compartment of mouse striatum

In spite of a clear genetic link between Parkinson's disease (PD) and mutations in LRRK2, cellular localization and physiological function of LRRK2 remain debated. Here we demonstrate the immunohistochemical localization of LRRK2 in adult mouse and early postnatal mouse brain development. Antib...

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Bibliographic Details
Main Authors: Wim Mandemakers, An Snellinx, Michael J. O'Neill, Bart de Strooper
Format: Article
Language:English
Published: Elsevier 2012-12-01
Series:Neurobiology of Disease
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996112002653