Randomized trial of time-limited interruptions of protease inhibitor-based antiretroviral therapy (ART) vs. continuous therapy for HIV-1 infection.

Randomized trial of time-limited interruptions of protease inhibitor-based antiretroviral therapy (ART) vs. continuous therapy for HIV-1 infection.

The clinical outcomes of short interruptions of PI-based ART regimens remains undefined.A 2-arm non-inferiority trial was conducted on 53 HIV-1 infected South African participants with viral load <50 copies/ml and CD4 T cell count >450 cells/µl on stavudine (or zidovudine), lamivudine and lopi...

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Bibliographic Details
Main Authors: Cynthia Firnhaber, Livio Azzoni, Andrea S Foulkes, Robert Gross, Xiangfan Yin, Desiree Van Amsterdam, Doreen Schulze, Deborah K Glencross, Wendy Stevens, Gillian Hunt, Lynn Morris, Lawrence Fox, Ian Sanne, Luis J Montaner
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3125169?pdf=render

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http://europepmc.org/articles/PMC3125169?pdf=render

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