Rapid and Efficient Conversion of Human Fibroblasts into Functional Neurons by Small Molecules

Summary: Recent studies have demonstrated that human astrocytes and fibroblasts can be directly converted into functional neurons by small molecules. However, fibroblasts, as a potentially better cell resource for transplantation, are not as easy to reprogram as astrocytes regarding their fate to ne...

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Bibliographic Details
Main Authors: Yaming Yang, Ruiguo Chen, Xianming Wu, Yannan Zhao, Yongheng Fan, Zhifeng Xiao, Jin Han, Le Sun, Xiaoqun Wang, Jianwu Dai
Format: Article
Language:English
Published: Elsevier 2019-11-01
Series:Stem Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2213671119303364