A novel statistical method for assessing effective adherence to medication and calculating optimal drug dosages.

We derive a novel model-based metric for effective adherence to medication, and validate it using data from the INhaler Compliance Assessment device (INCATM). This technique employs dose timing data to estimate the threshold drug concentration needed to maintain optimal health.The parameters of the...

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Bibliographic Details
Main Authors: Garrett Greene, Richard W Costello, Breda Cushen, Imran Sulaiman, Elaine Mac Hale, Ronan M Conroy, Frank Doyle
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5909911?pdf=render