Hybrid Multimodal Imaging Synthons for Chemoselective and Efficient Biomolecule Modification with Chelator and Near-Infrared Fluorescent Cyanine Dye

Hybrid Multimodal Imaging Synthons for Chemoselective and Efficient Biomolecule Modification with Chelator and Near-Infrared Fluorescent Cyanine Dye

The development of hybrid multimodal imaging synthons (MIS), carrying in addition to a chelator for radiometal labeling also a near-infrared (NIR) fluorescent cyanine dye was the aim of this work. The MIS should be introducible into biomolecules of choice via an efficient and chemoselective click ch...

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Bibliographic Details
Main Authors: Ralph Hübner, Valeska von Kiedrowski, Vanessa Benkert, Björn Wängler, Ralf Schirrmacher, Roland Krämer, Carmen Wängler
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:Pharmaceuticals
Subjects:
chelator
click chemistry
cyanine dye
<sup>68</sup>Ga<sup>3+</sup>
GRPR affinity
multimodal imaging
Online Access:https://www.mdpi.com/1424-8247/13/9/250

Internet

https://www.mdpi.com/1424-8247/13/9/250

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