A single-parasite transcriptional atlas of Toxoplasma Gondii reveals novel control of antigen expression

Toxoplasma gondii, a protozoan parasite, undergoes a complex and poorly understood developmental process that is critical for establishing a chronic infection in its intermediate hosts. Here, we applied single-cell RNA-sequencing (scRNA-seq) on >5,400 Toxoplasma in both tachyzoite and bradyzo...

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Bibliographic Details
Main Authors: Yuan Xue, Terence C Theisen, Suchita Rastogi, Abel Ferrel, Stephen R Quake, John C Boothroyd
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2020-02-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/54129