Inhibition of c-Jun N-terminal Kinase Signaling Pathway Alleviates Lipopolysaccharide-induced Acute Respiratory Distress Syndrome in Rats

Inhibition of c-Jun N-terminal Kinase Signaling Pathway Alleviates Lipopolysaccharide-induced Acute Respiratory Distress Syndrome in Rats

Background: An acute respiratory distress syndrome (ARDS) is still one of the major challenges in critically ill patients. This study aimed to investigate the effect of inhibiting c-Jun N-terminal kinase (JNK) on ARDS in a lipopolysaccharide (LPS)-induced ARDS rat model. Methods: Thirty-six rats wer...

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Bibliographic Details
Main Authors: Jian-Bo Lai, Chun-Fang Qiu, Chuan-Xi Chen, Min-Ying Chen, Juan Chen, Xiang-Dong Guan, Bin Ouyang
Format: Article
Language:English
Published: Wolters Kluwer 2016-01-01
Series:Chinese Medical Journal
Subjects:
Acute Respiratory Distress Syndrome; c-Jun N-terminal Kinase Inhibitor; Lung Inflammation C14H8N2O
Online Access:http://www.cmj.org/article.asp?issn=0366-6999;year=2016;volume=129;issue=14;spage=1719;epage=1724;aulast=Lai

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http://www.cmj.org/article.asp?issn=0366-6999;year=2016;volume=129;issue=14;spage=1719;epage=1724;aulast=Lai

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