Tumor Restrictive Suicide Gene Therapy for Glioma Controlled by the FOS Promoter.

Effective suicide gene delivery and expression are crucial to achieving successful effects in gene therapy. An ideal tumor-specific promoter expresses therapeutic genes in tumor cells with minimal normal tissue expression. We compared the activity of the FOS (FBJ murine osteosarcoma viral oncogene h...

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Bibliographic Details
Main Authors: Jianqing Pan, Hao Wang, Xinmin Liu, Jiliang Hu, Weijian Song, Jie Luo, Shan Jiang, Fei Yan, Baojin Zhai
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4646428?pdf=render