Biological response of spontaneously hypertensive rats to the streptozotocin administration

The sensitivity of adult spontaneously hypertensive rats (SHR) to the diabetogenic effect of streptozotocin (STZ) was studied. The animals were subdivided into three groups: control (citrate buffer), streptozotocin 40 mg/kg or 50 mg/kg, and general biologic parameters were analyzed, in addition to s...

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Bibliographic Details
Main Authors: Virginia Alice Vieira da Costa, Lucia Marques Vianna
Format: Article
Language:English
Published: Instituto de Tecnologia do Paraná (Tecpar) 2008-02-01
Series:Brazilian Archives of Biology and Technology
Subjects:
SHR
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132008000100006