TH2BS11ph histone mark is enriched in the unsynapsed axes of the XY body and predominantly associates with H3K4me3-containing genomic regions in mammalian spermatocytes

Abstract Background TH2B is a major histone variant that replaces about 80–85% of somatic H2B in mammalian spermatocytes and spermatids. The post-translational modifications (PTMs) on TH2B have been well characterised in spermatocytes and spermatids. However, the biological function(s) of these PTMs...

Full description

Bibliographic Details
Main Authors: Iyer Aditya Mahadevan, Satyakrishna Pentakota, Raktim Roy, Utsa Bhaduri, Manchanahalli R. Satyanarayana Rao
Format: Article
Language:English
Published: BMC 2019-09-01
Series:Epigenetics & Chromatin
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13072-019-0300-y