Chloroquine treatment enhances regulatory T cells and reduces the severity of experimental autoimmune encephalomyelitis.

Chloroquine treatment enhances regulatory T cells and reduces the severity of experimental autoimmune encephalomyelitis.

BACKGROUND: The modulation of inflammatory processes is a necessary step, mostly orchestrated by regulatory T (Treg) cells and suppressive Dendritic Cells (DCs), to prevent the development of deleterious responses and autoimmune diseases. Therapies that focused on adoptive transfer of Treg cells or...

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Main Authors: Rodolfo Thomé, Adriel S Moraes, André Luis Bombeiro, Alessandro dos Santos Farias, Carolina Francelin, Thiago Alves da Costa, Rosária Di Gangi, Leonilda Maria Barbosa dos Santos, Alexandre Leite Rodrigues de Oliveira, Liana Verinaud
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3683039?pdf=render

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http://europepmc.org/articles/PMC3683039?pdf=render

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