Decreased expression of LRA4, a key gene involved in rhamnose metabolism, caused up-regulated expression of the genes in this pathway and autophagy in Pichia pastoris

Decreased expression of LRA4, a key gene involved in rhamnose metabolism, caused up-regulated expression of the genes in this pathway and autophagy in Pichia pastoris

Abstract In a previous study, we developed Pichia pastoris GS115m, an engineered strain with decreased expression of one key gene, LRA4, in rhamnose metabolism. P. pastoris GS115m/LacB was subsequently constructed via introducing a β-galactosidase gene, LacB, under the control of rhamnose-inducible...

Full description

Bibliographic Details
Main Authors: Jian Jiao, Shuai Wang, Hui Tian, Xinxin Xu, Yuhong Zhang, Bo Liu, Wei Zhang
Format: Article
Language:English
Published: SpringerOpen 2020-02-01
Series:AMB Express
Subjects:
Pichia pastoris
Rhamnose metabolism
Transcriptome
Autophagy
Online Access:http://link.springer.com/article/10.1186/s13568-020-00971-2

Internet

http://link.springer.com/article/10.1186/s13568-020-00971-2

Similar Items