Transcriptome Profiling Reveals Matrisome Alteration as a Key Feature of Ovarian Cancer Progression

Transcriptome Profiling Reveals Matrisome Alteration as a Key Feature of Ovarian Cancer Progression

Background: Ovarian cancer is the most lethal gynecologic malignancy. There is a lack of comprehensive investigation of disease initiation and progression, including gene expression changes during early metastatic colonization. Methods: RNA-sequencing (RNA-seq) was done with matched primary tumors a...

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Bibliographic Details
Main Authors: Sumegha Mitra, Kartikeya Tiwari, Ram Podicheti, Taruni Pandhiri, Douglas B. Rusch, Andrea Bonetto, Chi Zhang, Anirban K. Mitra
Format: Article
Language:English
Published: MDPI AG 2019-10-01
Series:Cancers
Subjects:
ovarian cancer
fallopian tube
primary tumor
metastasis
gene expression
sequencing
tumor microenvironment
matrisome
Online Access:https://www.mdpi.com/2072-6694/11/10/1513

Internet

https://www.mdpi.com/2072-6694/11/10/1513

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