Genetic background may contribute to the latitude-dependent prevalence of dermatomyositis and anti-TIF1-γ autoantibodies in adult patients with myositis

Genetic background may contribute to the latitude-dependent prevalence of dermatomyositis and anti-TIF1-γ autoantibodies in adult patients with myositis

Abstract Background The prevalence of dermatomyositis (DM) versus DM and polymyositis (PM) combined has been shown to be negatively associated with latitude. This observation has been attributed to increasing exposure to ultraviolet (UV) light towards the equator. In this study, we investigated whet...

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Bibliographic Details
Main Authors: Joanna E. Parkes, Simon Rothwell, Alexander Oldroyd, Hector Chinoy, Janine A. Lamb, The Myositis Genetics Consortium (MYOGEN)
Format: Article
Language:English
Published: BMC 2018-06-01
Series:Arthritis Research & Therapy
Subjects:
Dermatomyositis
Polymyositis
Anti-TIF1-γ
Anti-Mi-2
Latitude
Ultraviolet light
Online Access:http://link.springer.com/article/10.1186/s13075-018-1617-9

Internet

http://link.springer.com/article/10.1186/s13075-018-1617-9

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