Dissociable effects of dopamine on neuronal firing rate and synchrony in the dorsal striatum

Previous studies showed that dopamine depletion leads to both changes in firing rate and in neuronal synchrony in the basal ganglia. Since dopamine D1 and D2 receptors are preferentially expressed in striatonigral and striatopallidal medium spiny neurons, respectively, we investigated the relative c...

Full description

Bibliographic Details
Main Authors: John M Burkhardt, Xin Jin, Rui M Costa
Format: Article
Language:English
Published: Frontiers Media S.A. 2009-10-01
Series:Frontiers in Integrative Neuroscience
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/neuro.07.028.2009/full