Current understanding of the molecular mechanisms in Parkinson's disease: Targets for potential treatments

Current understanding of the molecular mechanisms in Parkinson's disease: Targets for potential treatments

Abstract Gradual degeneration and loss of dopaminergic neurons in the substantia nigra, pars compacta and subsequent reduction of dopamine levels in striatum are associated with motor deficits that characterize Parkinson’s disease (PD). In addition, half of the PD patients also exhibit frontostriata...

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Bibliographic Details
Main Authors: Panchanan Maiti, Jayeeta Manna, Gary L. Dunbar
Format: Article
Language:English
Published: BMC 2017-10-01
Series:Translational Neurodegeneration
Subjects:
Parkinson’s disease
Neurodegeneration
Protein misfolding
Molecular chaperones
Cell therapy
Online Access:http://link.springer.com/article/10.1186/s40035-017-0099-z

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http://link.springer.com/article/10.1186/s40035-017-0099-z

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