Vasculogenic mimicry formation in EBV-associated epithelial malignancies

Vasculogenic mimicry formation in EBV-associated epithelial malignancies

EBV latent infection contributes to the pathogenesis of epithelial malignancies by inducing angiogenesis. Here, the authors show EBV promotes vasculogenic mimicry in EBV associated epithelial cancers via AKT/HIF-1α pathway and combination therapy of HIF-1α and VEGF reduces tumour growth.

Bibliographic Details
Main Authors: Tong Xiang, Yu-Xin Lin, Wenlong Ma, Hao-Jiong Zhang, Ke-Ming Chen, Gui-Ping He, Xiao Zhang, Miao Xu, Qi-Sheng Feng, Ming-Yuan Chen, Mu-Sheng Zeng, Yi-Xin Zeng, Lin Feng
Format: Article
Language:English
Published: Nature Publishing Group 2018-11-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-018-07308-5

Internet

https://doi.org/10.1038/s41467-018-07308-5

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