One-Pot Metal-Free Synthesis of 3-CF<sub>3</sub>-1,3-Oxazinopyridines by Reaction of Pyridines with CF<sub>3</sub>CO-Acetylenes

One-Pot Metal-Free Synthesis of 3-CF<sub>3</sub>-1,3-Oxazinopyridines by Reaction of Pyridines with CF<sub>3</sub>CO-Acetylenes

The reaction of pyridines with trifluoroacetylated acetylenes was investigated. It was found that the reaction of various pyridines with two molecules of CF<sub>3</sub>CO-acetylenes proceeds under mild metal-free conditions. As a result, efficient stereoselective synthesis of 3-arylethyn...

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Bibliographic Details
Main Authors: Vasiliy M. Muzalevskiy, Zoia A. Sizova, Kseniya V. Belyaeva, Boris A. Trofimov, Valentine G. Nenajdenko
Format: Article
Language:English
Published: MDPI AG 2019-10-01
Series:Molecules
Subjects:
pyridine
cf<sub>3</sub>co-acetylenes
1,3-oxazines
fluorinated heterocycles
Online Access:https://www.mdpi.com/1420-3049/24/19/3594

Internet

https://www.mdpi.com/1420-3049/24/19/3594

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