TERRA Expression Levels Do Not Correlate With Telomere Length and Radiation Sensitivity in Human Cancer Cell Lines

TERRA Expression Levels Do Not Correlate With Telomere Length and Radiation Sensitivity in Human Cancer Cell Lines

Mammalian telomeres are transcribed into long non-coding telomeric RNA molecules (TERRA) that seem to play a role in the maintenance of telomere stability. In human cells, CpG island promoters drive TERRA transcription and are regulated by methylation. It was suggested that the amount of TERRA may b...

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Bibliographic Details
Main Authors: Alexandra eSmirnova, Riccardo eGamba, Lela eKhoriauli, Valerio eVitelli, Solomon G Nergadze, Elena eGiulotto
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-05-01
Series:Frontiers in Oncology
Subjects:
clonal variation
TERRA
telomere length
radiation sensitivity
cancer cell lines
Online Access:http://journal.frontiersin.org/Journal/10.3389/fonc.2013.00115/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fonc.2013.00115/full

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