Collagenolytic activities of the major secreted cathepsin L peptidases involved in the virulence of the helminth pathogen, Fasciola hepatica.

Collagenolytic activities of the major secreted cathepsin L peptidases involved in the virulence of the helminth pathogen, Fasciola hepatica.

BACKGROUND: The temporal expression and secretion of distinct members of a family of virulence-associated cathepsin L cysteine peptidases (FhCL) correlates with the entry and migration of the helminth pathogen Fasciola hepatica in the host. Thus, infective larvae traversing the gut wall secrete cath...

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Bibliographic Details
Main Authors: Mark W Robinson, Ileana Corvo, Peter M Jones, Anthony M George, Matthew P Padula, Joyce To, Martin Cancela, Gabriel Rinaldi, Jose F Tort, Leda Roche, John P Dalton
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC3071364?pdf=render

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http://europepmc.org/articles/PMC3071364?pdf=render

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