Acute metabolic decompensation due to influenza in a mouse model of ornithine transcarbamylase deficiency

The urea cycle functions to incorporate ammonia, generated by normal metabolism, into urea. Urea cycle disorders (UCDs) are caused by loss of function in any of the enzymes responsible for ureagenesis, and are characterized by life-threatening episodes of acute metabolic decompensation with hyperamm...

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Bibliographic Details
Main Authors: Peter J. McGuire, Tatiana N. Tarasenko, Tony Wang, Ezra Levy, Patricia M. Zerfas, Thomas Moran, Hye Seung Lee, Brian J. Bequette, George A. Diaz
Format: Article
Language:English
Published: The Company of Biologists 2014-02-01
Series:Disease Models & Mechanisms
Subjects:
Online Access:http://dmm.biologists.org/content/7/2/205