Zika virus pathogenesis in rhesus macaques is unaffected by pre-existing immunity to dengue virus

Zika virus pathogenesis in rhesus macaques is unaffected by pre-existing immunity to dengue virus

Antibodies against dengue virus (DENV) can increase Zika virus (ZIKV) infectionin vitro, but their role in vivoremains largely unknown. Here, the authors show that pre-existing immunity from a 2.8 years earlier DENV infection does not affect ZIKV pathogenesis in macaques but instead shortens Zika vi...

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Bibliographic Details
Main Authors: Petraleigh Pantoja, Erick X. Pérez-Guzmán, Idia V. Rodríguez, Laura J. White, Olga González, Crisanta Serrano, Luis Giavedoni, Vida Hodara, Lorna Cruz, Teresa Arana, Melween I. Martínez, Mariah A. Hassert, James D. Brien, Amelia K. Pinto, Aravinda de Silva, Carlos A. Sariol
Format: Article
Language:English
Published: Nature Publishing Group 2017-06-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/ncomms15674

Internet

https://doi.org/10.1038/ncomms15674

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