NHEJ pathway is involved in post-integrational DNA repair due to Ku70 binding to HIV-1 integrase

NHEJ pathway is involved in post-integrational DNA repair due to Ku70 binding to HIV-1 integrase

Abstract Background HIV-1 integration results in genomic DNA gaps that are repaired by cellular DNA repair pathways. This step of the lentiviral life cycle remains poorly understood despite its crucial importance for successful replication. We and others reported that Ku70 protein of the non-homolog...

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Bibliographic Details
Main Authors: Ekaterina Knyazhanskaya, Andrey Anisenko, Olga Shadrina, Anastasia Kalinina, Timofei Zatsepin, Arthur Zalevsky, Dmitriy Mazurov, Marina Gottikh
Format: Article
Language:English
Published: BMC 2019-11-01
Series:Retrovirology
Subjects:
HIV-1
Integrase
NHEJ
Ku70
DNA-PK
Post integrational gap repair
Online Access:http://link.springer.com/article/10.1186/s12977-019-0492-z

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http://link.springer.com/article/10.1186/s12977-019-0492-z

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