PROSPER: an integrated feature-based tool for predicting protease substrate cleavage sites.

The ability to catalytically cleave protein substrates after synthesis is fundamental for all forms of life. Accordingly, site-specific proteolysis is one of the most important post-translational modifications. The key to understanding the physiological role of a protease is to identify its natural...

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Bibliographic Details
Main Authors: Jiangning Song, Hao Tan, Andrew J Perry, Tatsuya Akutsu, Geoffrey I Webb, James C Whisstock, Robert N Pike
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3510211?pdf=render