Specificity Studies of the Venezuelan Equine Encephalitis Virus Non-Structural Protein 2 Protease Using Recombinant Fluorescent Substrates

Specificity Studies of the Venezuelan Equine Encephalitis Virus Non-Structural Protein 2 Protease Using Recombinant Fluorescent Substrates

The non-structural protein 2 (nsP2) of alphavirus Venezuelan equine encephalitis virus (VEEV) is a cysteine protease that is responsible for processing of the viral non-structural polyprotein and is an important drug target owing to the clinical relevance of VEEV. In this study we designed two recom...

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Bibliographic Details
Main Authors: Beáta Bozóki, János András Mótyán, Gyula Hoffka, David S. Waugh, József Tőzsér
Format: Article
Language:English
Published: MDPI AG 2020-10-01
Series:International Journal of Molecular Sciences
Subjects:
VEEV
Venezuelan equine encephalitis virus
non-structural protein
nsP2
protease
alphavirus
Online Access:https://www.mdpi.com/1422-0067/21/20/7686

Internet

https://www.mdpi.com/1422-0067/21/20/7686

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