Inhibitory action of antioxidants (ascorbic acid or α-tocopherol) on seizures and brain damage induced by pilocarpine in rats Ação inibitória de antioxidantes (ácido ascórbico e α-tocoferol) nas convulsões e dano cerebral em ratos induzidos pela pilocarpina

Inhibitory action of antioxidants (ascorbic acid or α-tocopherol) on seizures and brain damage induced by pilocarpine in rats Ação inibitória de antioxidantes (ácido ascórbico e α-tocoferol) nas convulsões e dano cerebral em ratos induzidos pela pilocarpina

Temporal lobe epilepsy is the most common form of epilepsy in humans. Oxidative stress is a mechanism of cell death induced by seizures. Antioxidant compounds have neuroprotective effects due to their ability to inhibit free radical production. The objectives of this work were to comparatively study...

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Bibliographic Details
Main Authors: Adriana da Rocha Tomé, Paulo Michel Pinheiro Ferreira, Rivelilson Mendes de Freitas
Format: Article
Language:English
Published: Academia Brasileira de Neurologia (ABNEURO) 2010-06-01
Series:Arquivos de Neuro-Psiquiatria
Subjects:
crises epilépticas
estado de mal epiléptico
pilocarpina
ácido ascórbico
α-tocoferol
seizures
status epilepticus
pilocarpine
ascorbic acid
α-tocopherol
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2010000300005

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2010000300005

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