Suppression of Schistosoma japonicum Acetylcholinesterase Affects Parasite Growth and Development

Suppression of Schistosoma japonicum Acetylcholinesterase Affects Parasite Growth and Development

To further investigate the importance of Schistosoma japonicum acetylcholinesterase (SjAChE) in cholinergic signaling for parasite growth and development, we used RNA interference (RNAi) to knock-down its expression in adults and eggs in vitro. This resulted in its reduced transcription but also exp...

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Bibliographic Details
Main Authors: Hong You, Chang Liu, Xiaofeng Du, Sujeevi Nawaratna, Vanessa Rivera, Marina Harvie, Malcolm Jones, Donald P. McManus
Format: Article
Language:English
Published: MDPI AG 2018-08-01
Series:International Journal of Molecular Sciences
Subjects:
Schistosoma japonicum
zoonotic schistosomiasis japonica
acetylcholinesterase
RNA interference
vaccine target
Online Access:http://www.mdpi.com/1422-0067/19/8/2426

Internet

http://www.mdpi.com/1422-0067/19/8/2426

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