Serum Concentrations and Gonadal Expression of INSL3 in Eighteen Males With 45,X/46,XY Mosaicism

Serum Concentrations and Gonadal Expression of INSL3 in Eighteen Males With 45,X/46,XY Mosaicism

ObjectiveInsulin-like factor 3 (INSL3) is produced in the testes and has been proposed as a circulating biomarker of Leydig cell capacity, but remains undescribed in 45,X/46,XY mosaicism. The aim was to examine serum concentrations and gonadal expression of INSL3 in 45,X/46,XY mosaicism.MethodsRetro...

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Bibliographic Details
Main Authors: Marie Lindhardt Ljubicic, Anne Jørgensen, Lise Aksglaede, John Erik Nielsen, Jakob Albrethsen, Anders Juul, Trine Holm Johannsen
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-08-01
Series:Frontiers in Endocrinology
Subjects:
INSL3
45,X/46,XY
LC-MS/MS
gonadal histology
immunohistochemistry
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2021.709954/full

Internet

https://www.frontiersin.org/articles/10.3389/fendo.2021.709954/full

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