The Economics of Reproducibility in Preclinical Research.

Low reproducibility rates within life science research undermine cumulative knowledge production and contribute to both delays and costs of therapeutic drug development. An analysis of past studies indicates that the cumulative (total) prevalence of irreproducible preclinical research exceeds 50%, r...

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Bibliographic Details
Main Authors: Leonard P Freedman, Iain M Cockburn, Timothy S Simcoe
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-06-01
Series:PLoS Biology
Online Access:http://europepmc.org/articles/PMC4461318?pdf=render